Cortisol - The Age Accelerator or the Death Hormone!

Excess Cortisol created by stress can:

Increase blood sugar which in turn stimulates the production of excess insulin (excess insulin leads to body cell destruction and excess fat storage)
Depress immune function, leading to frequent or prolonged sickness
Cause loss of muscle mass
Decrease bone density
Osteoporosis
Impair wound healing
Slow thyroid function
Increase and prolong appetite
Encourage fat storage in the abdomen that may be associated with serious chronic health concerns
Interfere with reproductive function
Create feelings of anxiety
Encourage depression
Promote tumour growth
Foster feelings of anger and frustration
Cortisol is known as the "death hormone". It prepares our body to die. While cortisol increases with age, growth hormones decrease, which causes us to age.

Increased levels of cortisol are caused by stress, environmental pollutants, and lifestyle. Factors that increase cortisol in the body are: CAFFEINE, SUGAR and CHOCOLATE, STRESS and PROZAC/ANTI-DEPRESSANTS.

Read the 108 Effects of Sugar and you'll understand why the FDA would classify sugar as drug! (According to the FDA, any substance that knowingly alters the bodily functions is a drug.) Use the healthy alternative to sugar: Agave Syrup and Stebia.

Three cups of coffee will keep elevated cortisol levels in your body for 18 hours. If you take your coffee with sugar, there is a 200% increase!

LAVENDER BLOCKS CAFFEINE - STRESS
Resent research at the University of Vienna, Austria, shows, lavender blunts stress levels by almost 100% in caffeine-dosed mice. So if you are a coffee lover, and also want longevity, smell your Lavender bottle after coffee :) Better yet, rethink your lifestyle choices.

PROZAC INCREASES CORTISOL OUTPUT 2-3 TIMES
DID YOU KNOW: Any anti-depressant drug (Prozac, Zoloft, Paxil, Lovan, Luvox, and more) contain as their chief ingredients MERCURY and CHLORINE! (Mercury is connected to Alzheimer's.)

If you take 1-1/2 pills of Prozac just ONE (1) time (never before and never again), you'll double your cortisol levels. To exercise 3 times a day is 8 times more effective than anti-depressants. A sugar pill is 20 times more effective than anti-depressants. Research confirms, Paxil shows a 700% increase of breast cancer.

To learn the shocking truth about the mind-altering anti-depressant drugs, read the book, Prozac - Panacea or Pandora, by Ann Blake Tracy, Ph.D.

Longevity Cultures Eat No Drugs
They eat:

Hunza (apricots)
Vilcabamba (citrus, pineapple)
Azerbijian (mulberry)
Tarahumara (mangos, papaya)
Ningxia People (wolfberry)


The Health Effects of Stress and Increased Cortisol

Stress causes chemical changes in the body that, left unchecked, can have negative effects on both mental and physical health. High levels of stress contribute to health issues as diverse as depression, insomnia, heart disease, skin disorders and headaches.

The Reason for Stress

Stress is actually the physical expression of our "Fight or Flight" survival mechanisms. A threatening or tense situation triggers a stress response, which prepares us to confront or flee a possible danger. This is a healthy response to immediate danger, such as confronting an assailant or running from a fire. Unfortunately, the stress response is also triggered by tense situations where physical action is not an option, such as an unreasonable boss, or traffic jams.

Stress can be divided into two subtypes: acute and chronic. Acute stress prepares us for fight or flight, and is generally short-term. Chronic stress lasts longer, and is the main cause of stress-related health problems.

Acute Stress

Acute stress is a short-term response by the body's sympathetic nervous system. How long acute stress lasts may vary—the response can last for a few minutes or a few weeks.

During an acute stress response, the adrenal medulla (part of the adrenal glands, two small glands located on top of each kidney) begins to release catecholamine hormones (including adrenaline and noradrenaline). In all, over seventeen different hormones are released during an acute stress response. These trigger several physical responses:

blood sugar levels rise
additional red blood cells are released (to carry extra
oxygen)
peripheral blood vessels
constrict
pulse quickens
blood pressure rises
digestion stops.

High cortisol levels and stress contribute to eczema, high blood pressure, hardening of the arteries, chronic migraine headaches, fatigue, insomnia, acne, hives, eating disorders, diahrrea or constipation, acid reflux disease, skin disorders, sore muscles, rhuematoid arthritis, colitis, irritable bowel, chron's disease and many more.


Chronic Stress and Cortisol Levels

Chronic stress occurs when continuous acute stress responses keep the body on alert continuously, negatively affecting health. The ongoing stress response causes the hypothalamus and pituitary gland (portions of the brain) to release a chemical known as ACTH (adrenocorticotropic hormone). ACTH, known as the "stress hormone" stimulates the adrenal gland to produce and release cortisol.

Cortisol is one of the hormones associated with waking and sleeping. Levels of cortisol naturally fluctuate during the day. Cortisol levels are highest in the morning and lowest at night. Higher levels of cortisol in the morning help us wake up.

When chronic stress stimulates cortisol production, the daily cycle of cortisol levels is disrupted. High levels of cortisol may occur at night. This can result in insomnia.

Stress and Your Health

Stress levels affect health, but the effects are not immediately seen. Imbalances of cortisol and other stress-related hormones weaken health over time. Practicing stress management techniques can help minimize the effects of stress on your health.

The Effects of Stress on the Immune System

Stress causes physiological changes that tend to weaken our immune system. When our immune system becomes compromised, our health can be negatively affected: infections and illness occur more frequently, and immune system disorders such as psoriasis and eczema can "flare up." Outbreaks of oral and genital herpes occur with greater frequency during times of stress.

Inflammatory Immune System Disorders: Psoriasis and Eczema

Psoriasis, eczema, and other inflammatory immune system disorders have been linked to stress. When inflammation occurs, cortisol and other glucocorticoid hormones trigger an anti-inflammatory reaction in the immune system. Stress interferes with the immune system's ability to respond to these hormones.

Symptoms of psoriasis and eczema worsen with stress. Stress has even been proven to hinder psoriasis treatment. Study results published in Archives of Dermatology (July 2003) reported that patients under stress took up to eight percent longer to respond to a standard psoriasis treatment. The study suggested that patients would respond to psoriasis treatment faster if they received psychiatric intervention for stress during treatment.

The relationship between stress and psoriasis or eczema is complex. Not only does stress make eczema worse, but eczema itself causes stress. The disfiguring nature of eczema, people's attitudes toward it, and the discomfort associated with the disease all cause stress for someone with eczema. Stress management must be combined with eczema or psoriasis treatment for treatments to be effective.

Stress Management and the Immune System

Stress aggravates psoriasis, eczema and immune system disorders, so stress management should reduce the symptoms associated with those disorders. Research into the relationship between rheumatoid arthritis and stress backs up this hypothesis. Clinical investigations indicate the symptoms of rheumatoid arthritis patients improve when patients practice stress-reducing techniques such as Tai Chi and meditation.

Stress and Caregiver Immune Systems

The effects of stress on immune system diseases, such as psoriasis and eczema, are well-researched. Stress can also weaken ordinary immune systems, interfering with the body's natural defenses. Infections and diseases occur more frequently and take longer to recover from.

A study on stress and the health of elderly caregivers examined how stress weakens the immune system. The study examined levels of interleukin-6 (IL-6, a protein of the cytokine family) in elderly caregivers. Higher IL-6 levels hinder the immune system process, contributing to arthritis, heart disease and other diseases. The stress of caregiving caused IL-6 levels to increase four times as quickly in elderly caregivers as in study participants who were under less stress.

Damage of Excess Cortisol:

Researchers at the National Institutes of Health in Bethesda, Maryland, and the U.S. Naval Postgraduate School in Monterey, California, have documented the negative effects of excess cortisol:

Cortisol & Immunity

A 1995 study by researchers at the Department of Psychiatry, University of Mainz, Germany, reviewed extensive literature concerning cortisol's immune-suppressing effects.
Cortisol strongly damped T-cell proliferation, crucial toward defending against virally-infected and mutated cells in the human body.
Hiemke C, et al. Circadian variations in antigen-specific proliferation of human T lymphocytes and correlation to cortisol production. Psychoneuroendocrinology. 1995; 20(3):335-42

Jabaaij L. et al. Immunologic, endocrine and psychological influences on cortisol-induced immunoglobulin synthesis in vitro. Psychoneuroendocrinology. 1993; 18(8):591-605.

Cortisol & Osteoperosis

A study published in The Lancet compared hormone levels in women who experienced very fast bone loss with those who enjoyed very slow bone loss.
The only significant difference found was that women who lost bone rapidly had markedly higher cortisol levels.
Manolagas Sc, Anderson DC, et al. Glucocorticoids regulate the concentration of 1, 25-dihydroxycholecalciferol receptors in bone. Nature. 1979 Jan 22;277 (5694):314-5.

Manolagas SC, Anderson DC, Lindsay R. Adrenal steroids and the development of osteoporosis in oophorectomised women. Lancet. 1979 Sep 22;2 (8143):597-600.

Cortisol & Fat Accumulation

Cortisol activates fat-storage enzymes in cells.
Researchers at the Sahlgren's Hospital in Sweden identified a direct link between cortisol levels and midsection obesity.
The higher the cortisol level, the greater the fat accumulation and waist-to-hip ratio.
According to National Institutes of Health scientists, "Fat storage is enhanced by an increase in activity of LPL, the activity of which is stimulated by prolonged exposure to high tissue levels of cortisol in combination with insulin."
Marin P, Cortisol secretion in relation to body fat distribution in obese premenopausal women. Metabolism. 1992 Aug;41(8):882-6

Peeke PM, Chrousos GP. Hypercortisolism and obesity. Ann NY Acad Sci. 1995 Dec 29;771:665-76.

Cortisol Adds Appetite

Researcher Elissa Epel also documented the link between stress, cortisol and central body fat in 59 premenopausal women.
She noted that women who experienced the most stress-and cortisol output-were those who also had the most midsection fat.
In another study Epel noted that high cortisol levels had another undesirable effect: amped up appetite.
Epel ES et al. Stress & Body shape: stress-induced cortisol secretion is consistently greater among women with central fat. Psychosom Med. 2000 Sep-Oct;62(5):623-32.

Epel E et al. Stress may add bite to appetite in women: a laboratory study of stress-induced cortisol and eating behavior. Psychoneuroendocrinology. 2001 Jan; 26(1):37-49.

Cortisol & Impaired Memory

Researchers at the Bowman Gray School of Medicine of Wake Forest University in North Carolina validated the ability of cortisol on impairing memory and damaging brain cells.
University of Wisconsin researchers also linked stress-induced excess cortisol to brain damage.
They reviewed literature in which subjects with extremely high cortisol levels later developed psychiatric disorders and cerebral cortical atrophy observed in CT scans.
Kerr DS chronic stress-induced acceleration of electrophysiologic and morphometric biomarkers of hippocampal aging. J Neurosci. 1991 May;11(5):1316-24.

Jensen, Genefke, Hyldebrandt, Pedersen, Petersen and Weile, 1982. Uno H et al. Neurotoxicity of glucocorticoids in the primate brain. Horm Behav. 1994 Dec; 28(4):336-48.

Caffeine & Cortisol

15 ounces of coffee can double adrenaline production, which leads to increased cortisol.
Coffee can also increase noradrenaline levels, which raises blood pressure and increases heart rate.
Sugar & Cortisol

According to John Yudkin, MD, two weeks of consuming a high-sugar diet can increase both insulin and cortisol levels.
His research showed that fasting insulin levels increased 40% and cortisol levels shot up 300-400%.
Cortisol & Stress

Researchers at UCLA have shown that stress is one of the strongest instigators of excess cortisol.
Other studies have similarly documented the sustained rise in cortisol that occurs during period of high stress.
Futterman AD et al. Immunological and physiological changes associated with induced positive and negative mood. Psychosom Med. 1994 Nov-Dec;56(6):499-511.

Cortisol & Prozac

Studies at the University of Colorado and Greenslopes Private Hospital in Brisbane, Australia, showed that Prozac (fluoxetine) increases both cortisol and ACTH levels.
Research at the Vanderbilt University School of Medicine in Nashville, Tennessee, also documented the cortisol-boosting effects of Prozac.
Laudenslager ML, Clarke AS. Antidepressant treatment during social challenge prior to 1 year of age affects immune and endocrine responses in adult macaques. Psychiatry Res. 2000 Jul 24;95(1):25-34.

Torpy DJ et al. Diurnal effects of fluoxetine and naloxone on the human hypothalamic-pituitary-adrenal axis. Clin Exp Pharmacol Physiol. 1997 June; 24 (6):421-3

Meltzer H et al. Fluoxetine, but not tricyclic antidepressants, potentiates the 5-hydroxytryptophan-mediated increase in plasma cortisol and prolactin secretion in subjects with major depression or with obsessive compulsive disorder. Neuropsychopharmacology. 1997 Jul; 17(1):1-11.

How to Reduce Excess Cortisol

Reduce stress
Eliminate caffeine
Minimize sugar consumption
Increase vitamin C uptake
Resistance weight training to increase Hgh
Vitamin C Combats Cortisol Overload

New research documents the benefits of sustained-release vitamin C on hormone levels.
Researchers at the University of Trier in Germany found that patients receiving 1 gram three times a day of vitamin C (ascorbic acid) enjoyed markedly lower blood pressure and cortisol levels.
Vitamin C vs. Cortisol

A 2001 University of Pretoria study found that 500 mg. of vitamin C (ascorbic acid) taken twice a day reduced serum cortisol levels by over 30%.
Studies at Complutense University also found that women who supplemented their diet with 1 gram of vitamin C had markedly lower cortisol levels.
The drop in cortisol was especially pronounced in women suffering from heart disease.
De la Fuente M et al. Immune function in aged women in improved by ingestion of vitamins C and E. Can J Physiol Pharmacol. 1998 Apr;76(4):373-80.

Peters EM, Anderson R. Theron AJ. Attenuation of increase in circulating cortisol and enhancement of the acute phase protein response in vitamin C-supplemented ultramarathoners. Int. J Sports Med 2001 Feb;22(2):120-6.

Exercise & Growth Hormone

Sustained high-intensity exercise is one of the most effective natural growth hormone releasors.
Activities such as running and resistance training (weight lifting) have been shown to increase the quantity of growth hormone in the body by increasing the sensitivity of the hypothalamus.
Exercise is also key to maintaining low insulin & blood sugar levels. Both of these are important in triggering the release of the growth hormone.

PRIME ONE is one of the most effective natural products that block the effects of cortisol in the body. Contact our office for more information regarding PRIME ONE.

Disclaimer: This information is for educational and information purposes only and is not intended to replace the services of your health care provider (physician or veteranarian).

For information on this or any of our large selection of equine products contact:

Sharon Stebeleski, BPE, Irid. Herbalist
NATURALLY YOURS
Box 526 Lorette, Manitoba ROA OYO
(204) 878-2493
E-mail: info@healinghorsesnaturally.com
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