MSM - Organic Sulphur

A naturally Occuring Sulphur Compound used to alleviate pain in both humans and animals. It's safe, it's natural, it's nature's miracle; it's organic sulphur!

Is an effective natural analgesic and anti-inflammatory substance that provides a great benefit not only to the athlete but also to all that receive it.

In one standardbred study it showed a decrease in training times of 2.62 seconds (20 grams/day for 6 weeks then reduced to 10 grams per day). Other findings of the study:
an anti-inflammatory action as evidenced by the 56% reduction in thermal gradients
an analgesic effect upon the muscle tissue; recovery from exercise faster and an improved appetite ; improved hair coat and increased hoof growth

Sulphur occurs naturally on earth and is involved in almost every cell and process of the body. It is the third largest mineral in the body.

It softens cell walls allowing allergens, foreign proteins and any free radicals that have entered a cell to be allowed to be moved out of the body.
Because it is one of the ingredients used to make Glutathione, the master anti-oxidant made in the liver, it enables the recharging of the anti-oxidants vitamin c and e, so that they can continue to do their job.

The US government patents on sulphur confirm and prove it's effectiveness in areas such as:
a direct link between our sulphur level and rsistance to allergens
they confirm that we do not take suffecient amounts in our diet;
states it protects against stomach upset from things like aspirin, non-steroidal drugs and anti-inflammatory drugs; confirms that it keeps connective tissue and skin flexible

* It is considered important in our encorporation of important b vitamins.
* It helps to reduce the effects of sunburn and windburn and reactions to bug bites.
* It is necessary for collagen production in joints bones, hair, skin and nails.
* Can prevent cells from becoming rigid. Considered the anti-wrinkling mineral.
* Aids in the body's response to asthma, arthritis, inflammation, lupus, allergies, cancer, diabetes, digestive disorders, constipation, parasites, gum disease, sinusitis, burns, snoring, candida and much more.
* Has been shown to neutralize the lethal effects of common forms of pesticides.
* Is responsible for ionic exchange within the sodium-potassium pump in the cell.
* Assists in preventing dehydration of the body.
* Assists to detoxificy the body.
* Improves blood circulation.
* Helps control muscle cramps and back pain.
* Assists in recuperation from injury.
* Increases energy and alertness, mental calmness and the ability to concentrate.
* Decreases allergic reactions to foods and pollen.
* Minimizes acidity in the stomach and symptoms of ulcers and helps with hypersensitivity to drugs.
* Is a component of insulin; increases body's ability to regulate insulin and energy.
* Is needed for thiamin and biotin production which are needed for normal carbohydrate metabolism enabling gradual weight loss.
* Is necessary for the healing and repair of tissues.
* Is active against almost every class of parasite, because it coats the intestinal tract to prevent adhesion in the bowel.
* Is rated as one of the least toxic substancs in biology.
* Is not to be confused with sulfa-based drugs, sulfites, sulfates or sulfuric acid.

Sulfur is required in biochemical functions, such as in the formation of the cross bridges/links bettween collagen molecules which alters the formation of scar tissue; adding strength and stability to collagen rich tissues such as tendons, ligaments and joint tissues.

Sulphur is a part of every living tissue. We have it. We don't just have enough of it. Can we get enough of what our body needs from our diet? No. It is found only in raw fresh food. It is volatile and evaporates off into the air and is easily lost through cooking. Our foods are not eaten fresh enough. When you eat heat treated foods the sulphur has been dispelled. This applies to animals as well. The body uses it to continually create new healthy cells to replace old ones. It is structually and functionally important in more the 150 compounds in the body including tissues, enzymes, hormones, antibodies and antioxidants. The body is in a constant state of self repair, but if we do not have all the necessary ingredients, the end product is going to be less than perfect.

Specifically in horses.....it can asist with chronic problems such as slow wound healing, scar tissue, brittle hoofs, gastro-intestinal and lung problems , immune dysfunction, arthritis and to enhance performance and recovery from injuries and work-outs. It helps to promote healthy and flexible joints ,connective tissue and prevent OCD and joint
birth deformities. It has been shown to assist with the breakdown of calcium deposits.

THE SUPER SUPPLEMENT FOR HORSE AND RIDER.

Available in capsule and bulk powder. Pharmaceutical grade. 99.9% pure.

For information on this or any of our large selection of equine products contact:

Sharon Stebeleski, BPE, Irid. Herbalist
NATURALLY YOURS
Box 526 Lorette, Manitoba ROA OYO
(204) 878-2493
E-mail: info@healinghorsesnaturally.com
Visa Accepted

Article from the Natural Horse Vet

Nutritional Significance and Medical Applications of MSM® a biologically active sulfur compound

ABSTRACT: Methylsulfonylmethane (MSM®), a naturally occurring dietary derivative of DMSO, serves as an important source of bioavailable dietary sulfur and, when administered orally, is effective in ameliorating symptoms of physiological response to stress, including gastrointestinal upset, inflammation of the mucous membranes, pain associated with musculoskeletal system disorders, and infectant allergans. MSM® appears to augment immunological competence through a natural, vitamin-like moderating or normalizing activity for various body functions and is noted for its exceptionally non-toxic nature. MSM® has proven useful as a dietary supplement for both children and adults, including geriatric patients.

Methylsulfonylmethane (MSM®) is a naturally occurring, sulfur containing compound with multiple functions in the body. MSM® is naturally present in body fluids and tissues and is found in milk and a variety of fruits, vegetables, and grains in small amounts. At low levels of ingestion, it functions as a normal dietary ingredient and assimilable source of essential dietary sulfur. At higher levels it functions as a pharmaceutically active agent which can be used safely and effectively for a variety of purposes.
The development of MSM® as a dietary supplement stemmed from research on DMSO (dimethylsulfoxide). As a stable, odorless dietary metabolite of DMSO, MSM® possesses certain biomedical properties similar to DMSO together with additional biological activity not possessed by DMSO. MSM®, like DMSO, enhances urinary taurine secretion produced by aromatic hydrocarbons in man and neutralizes the toxicity of anticholinesterases, thereby providing protection against insecticide exposure or ingestion.

Nutritional implications of MSM®
MSM®, and many precursor compounds, which are readily converted to MSM® in the body, are found in most natural, unprocessed foods. However, because of its volatility, it is readily lost when fresh food is processed and/or stored. Unless the diet consists largely of raw, unprocessed foods, it is unlikely that sufficient MSM® will be ingested to contribute significantly to the daily nutritional sulfur requirement, thus furthering the high incidence of sulfur-deficient diets which exist globally.
Sulfur plays an indispensable role in human nutrition, which is often overlooked. It is responsible for the conformation of body proteins through the formation of disulfide bonds, thereby holding connective tissue together. Thiol (i.e. sulfhydryl) groups are vital for the catalytic function of several body enzymes. To perform these roles, constant intake of assimilable sulfur is needed by the body.
Although MSM® has not yet been established to be a vitamin, it does have a vitamin-like moderating or normalizing activity for various body functions, as there appears to be a high correlation between abnormal physiological symptoms and low MSM® blood levels in human beings. Although MSM® is found as a natural constituent of foodstuffs, like vitamin D., the principle supply is believed to be synthesized by the body using one of its naturally occurring precursor compounds. Also, excretion data show that MSM® occurs in lower concentrations with increasing age. Too low a body concentration of MSM® may potentially result in adverse physical and psychological stress, tissue and organ malfunction, fatigue, and increased susceptibility to disease.

Effects of oral administration of MSM®
Oral preparations of MSM have been found useful in the normalization of body functions in patients displaying physiological symptoms of stress, particularly those sources of stress which cause gastrointestinal upset, inflammation of mucous membranes, and allergic reactions. MSM® ameliorates these symptoms thereby permitting more rapid recovery.
Conditions, which have favorably responded to oral MSM® include the following:

ALLERGIC RESPONSES
MSM® has a broad and profound beneficial effect in ameliorating diverse allergic responses. MSM® ameliorates allergic reactions to inhalant, ingesting, contact and infectant allergens. Subjects find a direct correlation between concentration of MSM® used and resistance to allergens.
Environmental Allergies: Subjects with chronic to severe allergies to environmental materials such as house dust, pollen, wool, animal hair, feathers, and other diverse allergens report substantial to complete relief of their allergy symptoms after successive daily doses of MSM® varying from 50 to 1000 mg. per day. Allergy symptoms ranged from respiratory congestion to inflammation, itching, mucoid discharges, and general discomfort. Although MSM® alone may not totally eliminate allergic responses, the majority of subjects report a significant reduction in concurrent anti-allergy medication required to keep their allergic symptoms to a minimum. Individuals with allergic asthma or hay fever typically report equivalent or better control so symptoms with one-quarter or less of the prior required level of medication.
Food and Drug Allergies: Individuals who manifest an allergic response to drugs, such as aspirin, non-steroidal anti-arthritic agents (Indocin, Motrin) and oral antibiotics, as well as those who are mildly to severely allergic to various food, such as cereals, shrimp and other seafood, milk, etc., report either a lessened intolerance or a complete tolerance to these substances when ingesting 100 to 1000 mg. of MSM® concurrently. Thus, a major application of MSM may be as a safeguard against allergic response to orally ingested drugs, foods, or beverages, which are allergens or irritants to individuals sensitive to these substances.

GASTROINTESTINAL UPSET
MSM® is effective in ameliorating gastrointestinal upset such as that produced by in ingestion of aspirin and other pharmaceuticals or parasitic infections. Individuals with gastrointestinal symptoms such as diarrhea, chronic constipation, nausea, hyperacidity and/or epigastric pain, or inflammation of mucous membranes experience dramatic relief through the oral administration of 500-1500 mg. of MSM® daily.

PAIN ASSOCIATED WITH SYSTEMIC INFLAMMATORY DISORDERS
Individuals presenting signs and symptoms of pain and inflammation associated with various musculoskeletal system disorders, including arthritis, reported substantial and long-lasting relief while including from 100 to 5000 mg. of MSM® in their daily diet. Most, trying first MSM® alone, then a combination with ascorbic acid, reported greater benefit with the combination.
The use of MSM® with ascorbic acid is particularly useful in correcting night leg cramps. MSM® is capable of reduce the incidence of or entirely eliminating leg and back cramps., muscle spasms, and general soreness, particularly in geriatric patients who experience cramps at night or after long periods of inactivity. It is also effective for athletes who experience severe leg cramps during their sports activity. Migraine suffers have also obtained substantial relief at oral doses of 50 -500 mg MSM® per day while arthritic patients report relief for pain and stiffness as well as reduced swelling and inflammation.

PARASITIC INFECTIONS
In vitro and in vivo tests suggest that MSM® has ameliorating or curing activity against a variety of medically important parasitic, microbial, and fungal problems of the intestinal and urogenital tracts. MSM® is active against Giardia lamblia (traveler’s diarrhea), Trichomonas vaginalis, Nematodes, Enterobius and other intestinal worms, systemic infections by Histoplasma capsulation, Coccidioides, Toxoplasm and other in vitro susceptible organisms. Effective doses have been in the range of 750-1500 mg. per day. MSM® may affect such infections by competing for binding or receptor sites at the mucous membrane surface presenting a blocking interface between host and parasite. MSM® appears to augment immunological competence, which may also partly explain its effectiveness in treating parasitic infections.

Dosage and Administration Considerations
A single dose of MSM® is usually not effective in ameliorating symptoms. Thus, MSM® is usually administered periodically throughout the day or on successive days, or both. Noticeable results are usually seen within 2 to 21 days. The amount of MSM® in each dose is not critical. The usual individual dose is about 100-1000 mg., preferably 250-500 mg. Total daily dosages of 100-5000 mg., preferably 250-2000 mg. are usually employed.
The effective dosage depends to some extent on the nature and severity of symptoms manifested, the cause of those symptoms, and the MSM® blood level of the patient prior to administration. Healthy persons appear to have MSM® blood levels of at least 1 ppm, while patients displaying the above mentioned symptoms often have depressed MSM® blood levels. Blood sampling for MSM® however, is not ordinarily required because oral ingestion of amounts of MSM® in excess of that required to elevate MSM® blood levels is not harmful because of the non-toxic nature of MSM®.
Purified MSM® can be administered orally in any convenient manner, such as ingesting crystalline MSM® or its aqueous solution. Preferably, MSM® is given in oral dosage form such as tablets or capsules, each containing 100-500 mg. MSM®.
MSM® is of exceedingly low toxicity to all forms of plant and animal life. Except for its beneficial, inhibitory effect on cross-linking of collagen and proteins whereby it appears to be inert in tissues and body fluids. Because of its inertness, MSM® is nonallergenic, nonpyretic, and has no interfering or undesirable pharmacological effects. In fact, MSM® is especially suitable as a safe blood diluent because subjects do not react allergically to MSM® as they do when dextran is used. It can also be employed as a stable, neutral vehicle for pharmaceutical substances to deliver the pharmaceutical while simultaneously improving the condition of the patient’s connective tissue.

Summary
MSM® has important nutritional and medical implications for the maintenance of optimum health.

BIBLIOGRAPHY

Baker, DH: Utilization of Isomers and analogs of amino acids and other sulfur-containing compounds. Progress Food Nutr Sci 1986;10:133-178.

Herschler, RJ: Methylsulfonylmethane and methods of use. United States Patent 4,296,130; October 20, 1981.

Herschler, RJ: Dietary and pharmaceutical uses of methylsulfonylmethane and compositions comprising it. United States Patent 4,514,421; April 30, 1985.

Herschler, RJ: Methylsulfonylmethane in dietary products. United States Patent 4,616,039; October 7, 1986.

Jacob, SW and Herschler, RJ: Introductory remarks; dimethylsulfoxide after twenty years. Ann NY Acad Sci 1983; 411: xiii-xvii.

Pearson TW, Dawson HJ, and Lackey HB: Natural occurring levels of dimethylsulfoxide in selected fruits, vegetables, grains, and beverages. Am Chemical Soc 1981.

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